Exact(2)
The age estimates (Supplementary Table S5) based on 15 Y-STR loci variations (Supplementary Table S3, Supplementary Table S4 and Supplementary Table S7) were calculated using the method described in Zhivotovsky et al. 58 and updated in Sengupta et al. 18.
In experimental models of autoimmunity, there is evidence of a multistep process where subtle alterations resulting from quantitative trait loci variations accumulate with time, resulting in large changes in the susceptibility to autoimmunity when a threshold for the occurrence of the disease is passed.
Similar(58)
We analysed microsatellite loci variation in 1,769 fish sampled between 1995 and 2011.
We evaluated the role of selection in shaping immune-linked loci variation.
When information regarding genomic sequences is not rich, InDels polymorphism of tetraploid cotton species obtained by computational analysis might include both homologous and homoeologous loci variation.
For example, there is a high association of some microsatellite and MHC loci variation over Gila topminnows (Hedrick et al. 2001a), suggesting that stochastic factors appear important in the present spatial pattern of adaptive variation.
In addition to the between-cytotype variation in the number and distribution of 5S rDNA loci, variation in FISH signal intensity has frequently been observed (e.g., in the BB cytotype; Figure 2G).
The second type of variability was observed in different CpGs on the same locus (intra-loci variations).
Furthermore, this selection was based on analysis of single-locus variations, to account for redundancy [12].
The remaining seven Balimo isolates comprised two STs (ST667; n = 6 and ST668; n = 1), differing from each other by a single nucleotide polymorphism in the ace gene, but by four and five locus variations from ST267, respectively.
Although most loci were heavily methylated, there were some considerable inter-loci variations.
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