12– 14 The PCR amplification was performed on paired samples for parasite genotyping to distinguish between reinfection and recrudescence by using three parasite loci (merozoite surface protein 1, merozoite surface protein 2, and glutamate-rich protein).
Additionally, contingency loci affecting surface structures could be particularly significant from a clinical perspective when considering that outer membrane changes in C. jejuni have the potential to initiate autoimmune disease in the host, such as Guillain-Barré Guillain-Barré
burgdorferi loci (outer surface protein C [ ospC], 16S 23S rRNA (rrs-rrl-A), ospA, and outer membrane protein [ p66]) from strains isolated in the Northeast identified 9 distinct lineages with complete linkage among alleles at the 4 loci (10 ).
Gene duplication and loss as well as sequence variations at loci encoding surface-localized lipoproteins (e.g., the PF54 genes) are strongly associated with adaptive differences between species.
The great discrepancy between the constitutive locus-specific surface expression found amongst HLA-A,-B and -C could possibly be explained by translation attenuation by microRNA(s) specific for HLA-B (and possibly -C) alleles as it has been shown for HLA-G expression [37].
This stems from the strong adhesion of the encapsulating dielectric material to the metal, thus fixing the loci of the surface planes of the metal, which could result in mechanical damage through voiding, cracking or delamination.
Computed significance at the most activated cortical surface loci ranged from p < 10−5 to 10−10.
P. falciparum genetic diversity was investigated by using msp1 and msp2 encoding highly polymorphic loci from merozoite surface protein genes.
In Escherichia coli, homologous recombination is enhanced around loci coding for surface antigens, thereby increasing the effectiveness of recombination while minimizing its cost [ 32].
Scanning peptide arrays, mutagenesis studies and competition experiments with RACK1-derived peptides have identified probable loci on the surface of RACK1 that may contribute to protein-protein interfaces for some of RACK1's partners.
