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We observed that only 13 loci out of the 67 methylated loci were methylated in all RS samples.
And all SM samples were methylated at the same time in 18 loci out of 30 methylated loci, indicating less CpG-methylation variation in SM plants.
Two arbitrary criteria to assign haplotypes to different groups were applied, either 15 identical loci out of 16 or at least 11 identical loci [10].
No loci were out of HWE at more than one sample site, and 14 out of 18 sample sites did not have any loci out of HWE (Table 1).
The genes encoding HLA class I are among the most polymorphic in the human genome [12]: each individual expresses up to six different class I alleles (two at each of the A, B and C loci) out of a pool of over two thousand allelic variants defined to date.
This included 354 significant intergenic lncRNA loci (out of 647) and 69 significant antisense loci (out of 467).
Similar(5)
However, loss of one parental homeolog was observed at several loci (27 out of 46 homeologs), as were several examples of gene silencing (nine out of 34 homeologs).
Despite similarity in ID1-DBL2Xb allele repertoire across geographic areas, several peaks of strong population differentiation were observed at specific polymorphic loci, pointing out putative targets of humoral immunity subject to positive immune selection.
As both Class I and Class II loci turned out to be associated with MS, we based our subsequent analysis on investigating whether they are associated independently.
At present, polymorphisms in three dopaminergic loci stand out as the most frequently replicated molecular correlates of ADHD: DRD4, DRD5, and DAT [ 9, 10].
Unlinked regions in significant LD were more strongly linked to neighboring loci, ruling out the possibility that mis-assemblies underlie the patterns we observe.
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