Sentence examples for loci of target from inspiring English sources
Importantly, since shRNAs do not modify the genomic loci of target genes, the system enables transient, reversible gene silencing (Dow et al., 2012; Premsrirut et al., 2011), thereby facilitating genetic loss-of-function studies as well as an assessment of reversible and irreversible phenotypes simply by adding and removing dox from the diet.
Both these molecules exert primary functions downstream of the CDKs, loci of targets activity.
To further reduce the likelihood of integrating rep68 sequences into the AAVS1 locus of target cells, the rep68 expression module was designed in such a way that its FLPe-mediated activation is accompanied by its physical separation from the gene(s -of-interest.
Furthermore, 156 polymorphic loci of the target genes were mapped on the cotton genome.
HOTTIP belongs to the family of the "cis-acting" noncoding RNAs (that are embedded in the same genomic loci of their target genes) [ 94].
However, their mutagenic activity is not high enough to induce mutations at all loci of a target gene throughout an entire tadpole.
The prototypic trans-acting sRNAs of Enterobacteriaceae have a typical size between 50 and 200 nucleotides, are usually not genetically linked to the loci of their target genes and are often expressed under specific growth or stress conditions [ 1, 4].
We speculate that the different Rpfs perform similar functions in the cell (e.g. cell wall processing [ 32]) but at different loci of the target or with different efficiencies.
Mobile element insertion loci of the target subfamily are uniquely identified by their junction sequence, and all insertion junctions are linked to their individual libraries by the corresponding index sequence.
The results shed light on what genes were directly targeted and how PCFS4 might be recruited to the loci of those targets.
Mapping expression quantitative trait loci (eQTL) of targeted genes represents a powerful and widely adopted approach to identify putative regulatory variants.
