Finally, we find that long-range associations between loci located in different TADs are also detected, but these display much lower interaction frequencies than looping interactions within TADs.
In the case of Heliconius erato and Helconius melpomene, five major loci and several minor loci located on different chromosomes regulate multiple intraspecific wing colour patterns prevailing in the population45.
However, it is unclear whether a single locus or multiple loci located within this interval contributed to the effect.
These two sub-groups carry diagnostic alleles on at least two SSR loci located on different chromosomes, eliminating the possibility that this could result from miscoding.
Relevant with several findings of sterility loci located in this region, it is likely that male function contributes to hybrid barriers which may lead SD on chromosome 3.
V. cholerae has two higBA loci located on the chromosome II super-integron [53].
Tenaillon et al., [23] sequenced 21 loci located on chromosome 1 in 25 individuals including 16 exotic landraces and nine inbreds.
Antigenic variation occurs via unidirectional homologous recombination between the pilin coding gene (pilE) and one of many unexpressed pilS loci located at several sites on the gonococcal chromosome.
Loci located within a TAD mingle freely, but interact far less frequently with loci located outside their TAD.
More interestingly, loci located in centromeric regions tend to be more congruent with one another than loci located in telomeric regions.
Loci located within TADs tend to interact frequently with each other, but they interact much less frequently with loci located outside their domain.
