Most loci are specific to a single cancer type, and are often subtype specific (e.g. ER-positive breast cancer).
DSB peaks (prominent and weak) cover 22% of DNA within IGRs, prominent peaks cover 14% of DNA within IGRs, and 59 prl loci are specific to IGRs.
Three loci were specific for human and chimpanzee, one locus was present in orang-utan, chimpanzee and human.
Large-scale GWAS meta-analyses will be needed to establish more convincingly whether the identified obesity-susceptibility loci are specific to these ancestries or whether they are shared with other ancestries.
While five miRNAs bomiR-F02444, bomiR-A0321, bomiR-F2531, bomiR-D3011 bomiR-A37113711) were found to be conserved in at least two species, 21 miRNA loci were specific to bovine.
Among these, 488 SNP markers were commonly located on both linkage maps, while 157 and 148 marker loci were specific to the AMF2 map and the MMF2 map, respectively.
In human KIR haplotypes, a comparable number of genes are found in the centromeric (N = 8) and telomeric (N = 7) regions, indicating that recent gene expansion in the telomeric part of the KIR locus is specific to the human lineage.
The locus is specific to S. enterica ser.
This study confirms that the effect of IL-13 risk locus is specific for PsA, thus highlighting a key biological pathway that differentiates PsA from PsV.
This association demonstrated excellent consistency across the three Sikh samples, but no significant association was observed in a large East Asian replication study, indicating that the detected locus is specific to the Indian Punjabi Sikh population [ 37].
