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Interestingly, one of these two loci is located on cichlid LG5, on which the female heterogametic ZW locus and several quantitative trait loci (QTLs) related to adaptive evolution have been reported in Lake Malawi cichlids.
However, none of the experimental autoimmune encephalitis (EAE) loci is located close to the Cia40 linkage peak, indicating that other polymorphic genes might be of importance.
While we have no explanation for this phenomenon, it is interesting to note that each of these loci is located at or near the end of a linkage group; the associated supercontigs contain the genetic loci LF347, LF115, and AEGI8, respectively [ 5].
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Among the total 131 SSRs, most loci were located in intergenic spacer (IGS) regions (61.07%), followed by introns (23.37%) and CDS (17.56%) (Fig. 3b).
RASSF1A and BLU gene loci are located next to each other in the region 3p21.3.
Many miRNA gene loci are located within cancer-associated genomic regions.
In contrast, very few loci are located in the region for Module_3 and Module_7.
We have discussed the peculiarity of SZ genetics under the assumption that the risk loci are located in the ncDNA.
Only one CIS-associated miRNA locus overlaps a RefSeq protein-coding gene and six loci are located more than 10 kb from any RefSeq gene.
For example, if the isolation loci are located within or tightly linked to rearranged chromosomal regions, their fixation in different lineages can be significantly facilitated.
Only 3 of the 8 loci were located in coding regions in the S. aureus genome (Table 1 and Fig. 1).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com