Sentence examples for loci in primary from inspiring English sources

Methylation index (MI) was measured by absolute quantitative assessment of methylated alleles at seven MINT loci in primary CRC with contiguous adenomatous and normal tissues of 79 patients.

By delivering CRISPR/CRISPR-associated protein 9 (Cas9) ribonucleoprotein (RNP) complexes under conditions of rapid B cell expansion, we achieved site-specific gene disruption at multiple loci in primary human B cells (with editing rates of up to 94%).

HERV-W env sequences were encoded by multiple chromosomal encoding loci in primary human neurons compared with less chromosomal diversity in astrocytes and microglia (p<0.05).

For the capture experiment we targeted sequences in the Ig and TCR loci in primary lymphoid cancer samples, cancer cell lines and an EBV transformed cell line.

To examine whether some Alu insertions represented somatic events limited to recurrent ependymomas, which could have occurred in consequence of the loss of DNA methylation, we generated and compared PCR products from ten genomic loci in primary and in recurrent tumors derived from one individual.

Diaz-Llera S, Podlutsky A, Osterholm AM et al. Hydrogen peroxide induced mutations at the HPRT locus in primary human T-lymphocytes.

The CCR5 megaTAL nuclease established resistance to HIV in cell lines and disrupted the expression of CCR5 on primary human CD4+ T cells with a high efficiency, achieving up to 80% modification of the locus in primary cells as measured by molecular analysis.

We confirmed directly the epigenetic reprogramming at the EVC locus in primary ATL samples (Fig. 2f).

Our results show frequent LOH at the FAT locus in primary human glial tumors.

We previously reported up to 33% LOH at this locus in primary ATC (Kitamura et al, 2000a).

These interactions depend on the expression status of the genes such as the active β-globin locus in primary erythroid cells versus the same silent locus in fetal brain.