Your English writing platform
Discover LudwigSuggestions(1)
Exact(5)
Recently, new methods have been developed for investigating loci for selection by evaluating the extended haplotype homozygosity (EHH) associated with an allele [10], [18], [19].
Eight SNPs in our pared panel of 188 SNPs have been previously identified as a priori candidate loci for selection related to environmental variables.
Two approaches were used to detect candidate loci for selection based on either the empirical distribution of standardized heterozygosity (Kauer et al. 2003) or the simulated distribution of FST (Foll and Gaggiotti 2008).
The 23 microsatellites (21 new ones and two from the recommended panel) on BTA1 and BTA20 were chosen on the basis of their vicinity to genes and QTL, which could be considered as candidate loci for selection because of their assumed involvement in the polled/horned phenotype [ 22] and in milk yield and body composition [ 35].
Increasing the understanding of positive selection and how it shapes genetic variation in domestic animals has the potential to provide powerful insights into the mechanisms involved in evolution, help target loci for selection and possibly highlight the genetic basis of phenotypic diversity for complex traits [ 5, 11].
Similar(55)
Thus, the identification of favored alleles will help in choosing parents for crossing programs, to ensure maximum levels of favored alleles across sets of loci targeted for selection, and to promote fixation at these loci [ 63].
Though these substitutions could represent candidate loci for directional selection, statistical support is not strong.
In order to find the appropriate value of x* and t*, we can examine t* in t0 continuous possible values, ⌊ t/2⌋ − ⌊ t0/2⌋ ≤ t* ≤ ⌊ t/2⌋ + ⌊ t0/2⌋ and examine x* in all SNPs loci for each selection of t*.
The annotation of genome scaffolds that are linked to candidate loci for directional selection produced associations to genes connected to development rate, osmoregulatory function, and reproductive maturity (Tables 1 and 2).
Even though the 8p23 region harbors several candidate loci for natural selection (Pickrell et al. 2009), and genes related to autoimmune disorders (Deng and Tsao 2010), a model of neutral evolution shaped mostly by demographic factors has been suggested to explain its current distribution (Salm et al. 2012).
It is not known whether the identification of additional candidate loci for strong selection in the BI/NBH pair only suggests unique tolerance-related or biologically-relevant differences (BI is the only oceanic rather than estuarine site included in this analysis) or technical artifacts (statistical power).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com