Genotypes were only available for rs9306894 in the chromosome 2 locus and gene expression data had been obtained using RNASeq.
We have used sequence conservation data to link report pages with each other such that users can move from one locus (and its expression data) to its (most likely) ortholog within a single mouse click.
The locus specific gene expression data analysis was done by first mapping the Affymetrix probe sets to their corresponding genes in the mouse genome in Ensembl database version 43.
For example, while Hinds et al. performed GWAS to identify allergy-related loci in a sample of personal genetics company customers and birth cohort participants [ 9], they then identified expression quantitative trait loci (eQTL) among these loci using monocyte gene expression data from a distinct study cohort of heart disease.
The list of 1,583 gene loci and related gene expression data are presented in Table S1.
Quantitative Trait Loci (QTL), polymorphic and expression data were analysed alongside in silico workflow analyses to discover novel candidate genes central to the development and biology of chronic colitis.
The degree of methylation is usually denoted as β, ranging from 0 to 1. Methylation data are presented in the same matricial form of expression data (locus × sample), however, cautions must be used in the direct application of transcriptiomic analysis tool to methylation data.
We paired loci used in methylation analysis with gene expression data from the appropriate loci according to Entrez Gene ID.
YX, WM, EK, HH, BB, SB, and B-HK analyzed the Meg loci, their genomic region, and expression data.
In other studies, chromosome locations, protein-protein interactions, gene expression data, and loci distance were used to identify and rank candidate genes within disease networks [ 6- 9].
