In this work, CassTAS3, which is processed by the Xam-induced miR-390, was also found targeting ARFs, although the locus expression was not significantly increased.
Conversely, microarray or even EST evidence for locus expression is not certain evidence of a productive mRNA, particularly for data collected from conjugating cells with nongenic transcription.
Because the rate of evolutionary turnover of secondary sexual traits in particular is expected to be high (Holland and Rice, 1998), some loci affecting their expression are likely to experience sex-specific selection.
This could have important therapeutic applications as loci still able to express HbF might be more amenable to therapeutic up-regulation than loci where expression is nil.
Much progress has been made in the identification of a network of loci whose expression is modulated by EWS/FLI1 and its congeners.
Loci whose expression is in agreement with profiles of glucosinolates (figure 2, additional file 2, figure S1) and glucosinolate hydrolysis products (table 5) are highlighted in bold.
Given the additional heme required to maintain viability in strains R2846 and 86-028NP, these genes may represent loci whose expression is only altered under extreme FeHm stress.
We further restricted our selection to those loci whose expression was supported by cDNA, EST, or RNA-Seq data available in the TAIR database.
To this end, recent EWAS have found common epigenetic changes in pre- and post-symptomatic children with type 1 diabetes (T1D) [ 3], and differences in fresh cord blood at gene loci whose expression was associated with body mass index in late childhood [ 4].
In mice with the Sacytm1Lex locus, lacZ expression was only detected in testis, suggesting that at least the promoter and exon 1 are specific to male germ cells.
