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These candidate regions, called loci by geneticists, are often large and may contain many genes, any one of which could hold the suspect mutation.
However, expression cassettes containing the cbh1 promoter might integrate at the cbh1 loci by homologous recombination.
The CRISPR-associated endonuclease Cas9 can be targeted to specific genomic loci by single guide RNAs (sgRNAs).
Classical 3C can detect chromosome interaction between two interested loci by checking the ligation products with PCR using locus-specific primers (one to one).
Figure 3 Dendrogram of 55 tea germplasm in Taiwan using 39 STS and CAPS loci by UPGMA method based on modified Roger's distance coefficient.
Suitable voltage control was proven to provide a repeatable electro-kinetic injection of PCR product sufficient for an on-chip separation of multiple loci by capillary electrophoresis.
In our study, seventeen Greek patients, 2yo on average, were analyzed for the presence of pathogenic germline mutations in the aforementioned loci by Next-Generation Sequencing.
Generation of genetically engineered mouse models (GEMMs) for chromosomal translocations in the endogenous loci by a knockin strategy is lengthy and costly.
Deamination within the immunoglobulin loci by AICD initiates antibody gene diversification.
We compared the mapped loci by the poly A-, poly A+, and bimorphic 3' ESTs.
We next analyzed the interaction of ERα with target gene loci by performing chromatin immunoprecipitation (ChIP).
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