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An alternative interpretation of the findings from analyses using the 2-parameter model allows for gene flow to cease for all loci at the same time – i.e., it allows for a single SIM applicable to all loci.
There was no family found to have these two sex-determining loci at the same time.
It has been suggested that selection on such traits, termed polygenic selection, usually acts on standing variation at several loci at the same time.
The PCR products labelled with a fluorochrome were mixed together with GeneScan-500 ROX as internal standard to run the maximum of loci at the same time (considering the colour and the expected allele size range).
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Discussing a bit more the well known fact that sense and antisense transcripts are commonly expressed in cells, though not necessarily from the same locus at the same time.
2. Discussing a bit more the well known fact that sense and antisense transcripts are commonly expressed in cells, though not necessarily from the same locus at the same time.
The decrease in population size between large and small control populations (about 60% in the small control compared with the large control population) induced a slight increase in the percentage of polymorphic loci and, at the same time, a slight decrease in the average number of alleles per locus and the total number of rare alleles in the small control population.
This approach reduced concerns of spurious results due to sequencing error and/or repertoire inflation due to paralogous loci, but at the same time it is likely to underestimate the total number of genuine V1R paralogous copies.
While the first effect promotes increase of A1 and a simultaneous increase of the population fitness, the second effect enables a rapid change of the frequency structure at locus B but at the same time reduces the population fitness and especially the fitness of A1 A1 types, thus reducing the chances for establishment and fixation of coherence.
In 2008, a GWAS for waist circumference in 2,684 Indian Asians identified the locus near- MC4R [ 36] at the same time that this locus was identified for BMI in Europeans [ 16].
Our analysis enables us to investigate loci with pleiotropic effects and, at the same time, to investigate whether epigenetic or genetic effects are more important in explaining phenotypic variance in traits of interest.
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