Sentence examples for loci activation from inspiring English sources

In the 7-DAP endosperm, the parental siRNAs reached a normal dosage ratio of 2 m:1p, implying an early full paternal siRNA loci activation and a balanced siRNA biogenesis between the two parental genomes.

To address this question, and determine the critical events in locus activation that control RSS accessibility, our strategy was to activate V(D J recombination and then analyse the cascade of events that follow.

Ma S, Turetsky A, Trinh L et al. IFN regulatory factor 4 and 8 promote ig light chain kappa locus activation in pre-B cell development.

We have named the four stages as uninduced, locus activation, transcriptional activation and fully transcribed stages.

The holocomplex subsequently recruits the SWI/SNF chromatin remodeling complex, leading to locus activation.

lncRNA transcription, either by opening chromatin or inhibiting repressor protein binding, could similarly result in gene or locus activation.

Together, our data underpin the central role of non-coding transcription in regulating locus activation for V(D J recombination.

RSS accessibility is generated as part of the highly regulated, multistep process of locus activation for V(D J recombination.

The most notable point is that events on the LCR occur at a locus activation stage that is after transcriptional induction but before transcriptional activation of gene.

This implies that increased non-coding transcription is not essential for histone hyper-acetylation at these loci; it also indicates that acetylation is an early event in locus activation.

The finding that increased levels of IRF4 alone completely activate Igλ recombination in pro-B cells is striking and implies that IRF4 acts very early in the multistep process of locus activation.