Sentence examples for loci accessibility from inspiring English sources

This cannot be ascribed to intrinsic characteristics of the different targeted loci (accessibility and epigenetic modifications), indicating a distinctive higher efficiency of CRIPSR-I4 at inducing DSBs.

Auxin treatment failed to increase FIL and LFY locus accessibility, presence of activating histone marks, and gene expression in brm-3 syd-5 mutant inflorescences.

Histone acetylation has been linked with increased locus-wide accessibility (Hebbes et al, 1994) and, since acetyltransferases associate with elongating RNA polymerase II (Wittschieben et al, 2000), this seemed a potential candidate for increasing RSS accessibility.

From these combined data we conclude that distinctive histone modifications at myelin gene loci modulate the accessibility of TFs to DNA in distinct cell types.

We conclude that tethering of BRM or SYD complexes to MP target loci increases their accessibility and transcription.

The binding of BATF and IRF4 to those loci increases chromatin accessibility for other transcription factors, and it is prerequisite for Th17 differentiation.

Furthermore, quantitative trait locus mapping revealed chromatin accessibility differences at 1,325 loci associated with genotypic variants at a false discovery rate of 0.01.

This model includes the active involvement of erythroid transcription factors in the spatial organization of the locus, and increased accessibility to trans-acting factors by recruitment of chromatin remodeling complexes [5].

At IIIR the pattern closely resembles the non-repressed promoter structure observed at the native URA3 locus with increased MNase accessibility compared to the deproteinized DNA digest.

Numerous studies have shown that both the TRB enhancer (Eβ) and transcriptional promoters within the TRB locus serve as RAG accessibility control elements, playing a critical role in regulating chromatin structure and therefore recombination of TRB genes [ 21- 27].

We then normalized each loci to the percentage of accessibility in control siRNA treated cells.