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There was a significant difference between the loci above and below 200 bp in length.
An RPKM (Reads per Kilobase per Million) cut-off value of 0.1 was set to declare a locus expressed resulting in 32,862 and 32,778 loci above the expression cut-off for Eurosis and Loto varieties, respectively.
Thus, it could be stated that at least nine human-specific RRMI loci including the three loci above contribute to genomic variation within the human population.
Prunier et al. (2011) also identified 10 candidate loci above the 99% C.I. in black spruce.
A higher cutoff for the image or log scale coloring may highlight the major loci above the general noise.
This suggests that loci above nine repeats exhibit the dynamic mutational behavior characteristic of microsatellites (hyper- or microsatellite mutability).
Similar(44)
Although the other loci listed above are likely to be true T2D markers, the actual impact of these genetic variants in other European and non-European populations as well as their cumulative effects and potential interactions remain to be determined.
In addition to the presence of intact WD-40 repeats in the pseudogenes loci outlined above, a second observation suggested concerted evolution of the WD repeats of the NWD gene family.
Shared regions were defined as the segment of contiguous loci remaining above nominal statistical evidence.
Conserved genomic regions to the four human loci described above were identified in the M. musculus, X. tropicalis, G. gallus, F. rubripes, D. rerio and T. nigroviridis genomes.
A second multi-locus HKA test was performed using the "HKA" software distributed by Jody Hey [ 40] and the same reference loci reported above; 1000 coalescent simulations were performed with the cosi package [ 34].
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