Sentence examples for location of variations from inspiring English sources
As part of the Encode project, scientists identified the location of variations in DNA that have been linked to common diseases like cancer.
After determination of the location of variations across the genome, 2156 SNPs/indels were found within the genic region scattered over 87 genes in whole variations, including those encoding tRNAs and rRNAs (Table 1, Additional file 2: Table S2).
The search output includes the location of variations if present in the gene of interest.
This new dataset allowed us to precisely map the location of variation, to investigate whether variability is focused on precise nucleosomes or spread on many consecutive ones and to determine the degree of co-variation between marks on individual nucleosomes.
Pooling individual samples together prior to either whole-genome (e.g. Futschik and Schlotterer 2010) or reduced-representation (e.g. Vandepitte et al. 2012) sequencing is another approach that can greatly reduce costs, while still providing useful information about the genomic extent and location of variation and divergence.
Chromosomal locations of variations relative to the NCBI36 human genome assembly were downloaded from the Database of Genomic Variants (DGV) [45], [46].
Modeling the Q-rich region and the remaining C-terminal end of rat Sry shows the locations of variations outside of the HMG box mapped onto the structure of Sryα interacting with DNA.
We used Genome-wide Complex Trait Analysis to (1) estimate phenotypic variance explained by genetics; (2) calculate genetic variance explained by known AD single nucleotide polymorphisms (SNPs); and (3) identify the genomic locations of variation that explain the remaining unexplained genetic variance.
A brief description of these detectors and descriptors is given as follows: Space-time interest point: Given an action video, local space-time interest points (STIP) are detected around the location of large variations of image values, which corresponds to motions.
At present, Ensembl (Hubbard et al., 2009) can be used to retrieve the location of nucleotide variations, by installing the relevant APIs and locally running a perl script.
Motivation: Defining the precise location of structural variations (SVs) at single-nucleotide breakpoint resolution is an important problem, as it is a prerequisite for classifying SVs, evaluating their functional impact and reconstructing personal genome sequences.
