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There are a variety of mechanisms that can produce these products, depending on whether the strain is a haploid or diploid, the availability of repetitive sequences (for example, transposons) located near the break, the location of essential genes near the break, and other factors.
Spatial clustering of mutation rates is likely to have significant evolutionary consequences in shaping patterns of synonymous substitutions and the location of essential genes.
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The files also show GCHQ and Overhead developed their ability to track the location of individuals – essential for the targeted killing programme – in both Yemen and Pakistan.
One plausible explanation for this result would be the location of an essential gene on the opposite strand.
Indeed, if the system of basis functions (7) is chosen to correspond to the current location of the essential support, the total number of discretisation coefficients α i (t) will be small.
Most relevant to the catalytic mechanism is the fact that even though the secondary structural elements that form the active sites of the two thioesterases are highly conserved, the constellation of catalytic residues is dissimilar as is the spatial location of the essential catalytic carboxylate residue.
The critical need of refugee locations for essential services has been hampered by the lack of adequate funding through the 2011 Liberia Emergency Humanitarian Action Plan.
The first part shows how doing a complete statistical analysis of the fit of the model at the location of interest is essential for determining the reliability of the model data.
The limits of the inner ends of the observed deletions (between 32 and 38 kbp from the right-hand end of the CPV-BR genome) appear to be defined by the location of the nearest essential gene on the one hand and the location of the gene that encodes "pock redness" on the other.
Cytotoxic drug-induced autophosphorylation and changes in cellular location of Chk1 are essential for its full activation (Clarke and Clarke 2005; Löffler et al. 2007).
Mobile wireless provides for flexibility of location, essential for working people and parents, and coupled with a smart phone, mobile wireless can be a low-income family's most economic link to Internet services.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com