Our study aimed to investigate the influence of tumor location on dose quality and delivery efficiency of tomotherapy plans.
The combined approach could achieve superior performance in determining the anatomical location of therapeutic dose errors and in assessing the deviation of volumetric dose parameters, thus greatly improving the clinical applicability and effectiveness of quality control during radiotherapy.
Apart from the confirmation of efficacy, the acquired information may help to investigate the shape and location of the dose-response curve, the choice of an appropriate therapeutic starting dose, the identification of optimal strategies for individual dose adjustments, and the determination of a maximal dose beyond which additional benefit is unlikely to be obtained.
Similarly, the location of steep dose gradients provided by modern highly conformal radiotherapy or stereotactic radiosurgery allowing sparing of adjacent normal structures requires excellent definition of the soft tissue and bony extent of disease.
The dates, locations and dosing strategies of these 7 studies are summarized in Table 1.
145 TENS therapy is characterized by its electrical parameters, number and location of electrodes, and dosing schedule.
According to our result, we believe that the location of the distal dose edge can be determined within 1 2 mm from the distribution of the prompt gammas.
Our result is very encouraging, showing that there is a clear correlation between the distribution of the prompt gammas and the location of the distal dose edge for the 38 MeV proton beam.
Due to the location of the allograft, doses are usually reduced to prevent reported complications of proteinuria, acute and chronic renal failure [ 40].
Other relevant data, which was not available included information on the use, timing and location of a test dose, the decision-to-delivery interval, and details of asthma diagnosis and treatment.
It was also not possible to consider the effects of dose, location of the intervention, or study quality when conducting the meta-analyses.
