Sentence examples for location of binding sites from inspiring English sources

Unless the location of binding sites affects gene expression, it is not under any natural selection pressure.

(2) One molecule of a negative allosteric modulator (NAM), FITM, was found to bind in a pocket on the extracellular side of the 7-TM domain, which is in a similar location of binding sites of orthosteric ligands in class-A GPCRs.

The docked lipovitellin was used to infer the location of binding sites for three monoclonal antibodies that have been described [39].

As the third layer of correlation, we used phylogenetic footprinting to filter the HMM hits, extracting the location of binding sites near microarray gene hits that are also conserved across evolution.

The distribution of HLH-1 bound intervals relative to the TSS revealed the −200 to −400 bp region as the most frequent location of binding sites (Figure 1) and identified 1,032, of the predicted ∼20,000 (WS195) protein encoding genes, as potential targets of HLH-1 regulation (Table S2).

The sequence motif analysis serves to pinpoint the exact location of binding sites in potential target regions obtained by ChIP.

This observation also independently confirms the location of binding site for inhibitors.

Also, locations of binding sites identified by ChIP-chip or ChIP-seq are often overrepresented in the TSS vicinity (data not shown).

Cross-Linking Immunoprecipitation (CLIP) captures the in situ specificity of protein-RNA interaction and allows for the simultaneous identification of endogenous RNA targets as well as the locations of binding sites within the RNA transcript.

33 The HbHNL/ AtHNL pair can best be classified in group 3 that is, same protein folding with exchanged locations of binding sites.

Each PET sequence is mapped onto the genome and the locations of binding sites can be inferred by overlapping PET-defined clusters.