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I am interested in estimating the size, location and effects of trace gas emissions so that the largest emission sources can be identified and mitigation strategies can be developed.
Conventional QTL mapping is used to identify the location and effects of QTLs controlling traits of interest.
Their location and effects are randomly generated.
By estimating the naturally occurring pattern of adaptation, the effects of SNPs may be compared to the location and effects of extant genetic variation and historical adaptations within the broader taxonomic group.
This program uses mixed models and the maximum likelihood method to estimate the QTL location and effects.
Detailed analyses of the location and effects of viability mutations in the G0 families are reported elsewhere (L. V. Plough, G. Shin, and D. Hedgecock, unpublished data).
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The next great challenge of pharmacogenetics is to pin down the cellular location and effect of these variant proteins on the pathways and networks that govern individual variation in responses to drugs and other exogenous chemicals.
Hence, the ORs produced by GWAS are unlikely to represent the true effect sizes of the functional variant(s) which are only approximated, in both location and effect, by the tagSNPs genotyped in GWAS [4], [89].
They also provide separate estimates of QTL location and effect.
The location and effect of all metabolic QTLs identified from the CIM model are presented.
Syndromes are defined by symptom location and effect of mechanical loading.
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