To improve the annotations of genes located in regions interrupted by gaps in the genomic assembly, sequencing reads were used for reference guided transcript assembly.
The PKS gene cluster (PS11G3) was located on two contigs interrupted by a small gap, which was closed by primer walking.
As noted above, a study by Wang and colleagues demonstrates that inducible expression of 960 interrupted CUG repeats located in the DMPK 3'UTR sequence results in the development of nuclear foci concurrent with arrhythmias, cardiomyopathy, cystolic and diastolic dysfunction and aberrant splicing [24].
In our analyses, we were unable to locate K7 genes that were interrupted by a Ty insertion.
In the mouse genome, the reproduction-related Nlrps (except for Nlrp14) are not located side by side, but interrupted by some other types of genes, especially and mainly by certain V1r genes (discussed below) on chromosome 7A1 and 7A3.
The brothers locate and confront Dixon, but are interrupted by Gordon and fellow hunter Kubrick.
CA XIV in Fig. 1b (lower lane) shows punctate staining, which, as also seen in the merged image, is completely interrupted wherever triads are located.
In subtype A myosins, the tail is interrupted by a conserved intron located at the C-terminal end of the conserved C-terminal region 1 (see below).
The human ADAM10 gene is located on chromosome 15q21.3-q23 and contains 16 exons interrupted by 15 introns [ 24, 25].
MISA software (http://pgrc.ipk-gatersleben.de/misa/) was used to locate and identify both perfect microsatellites and compound microsatellites interrupted by a certain number of bases.
Treatment itself is available at a few sparsely located health centres and even then the availability of the drugs is interrupted during periods of limited stock, with the larger cities getting priority.
