Exact(1)
Grade I astrocytomas occur more in children, are curable by surgery and might represent a separate disease from the astrocytomas of other grades [ 3], however, virtually all high-grade astrocytomas eventually progress and locally relapse regardless of improved diagnosis and multi-modality treatment [ 4, 5].
Similar(59)
Here, we report quite a rare case in terms of long survivor after chemoradiotherapy on locally relapsed unresectable hilar cholangiocarcinoma.
Patients with histologically confirmed muscle invasive primary transitional cell carcinoma of the bladder and with locally relapsed, locally advanced or metastatic disease were eligible for the study.
The number of patients with at least a local relapse may reflect the absence of radiation either locally or through a TBI.
Local relapse.
HR: Hazard ratio; CI: Confidence interval; ECOG PS: Eastern Cooperative Oncology Group Performance Status RRResponsense rate; CR: Complete response; PR: Partial response; SD: Stable disease; PD: Progressive disease; Mets: metastasis; LA/LR: Locally advanced/local relapse.
Although chemotherapy remains the primary strategy in managing unresectable, locally advanced, relapsed, and metastatic PCs and BTCs, few chemotherapeutic options could demonstrate their benefits in significantly prolonging patients' progression free survival (PFS) and OS.
In July 2002, AstraZeneca plc opened an expanded access programme to provide single-agent gefitinib to patients with locally advanced, relapsed or metastatic head and neck cancer.
The study population consisted of consecutive patients with locally advanced, relapsed of metastatic gastric cancer who were treated with palliative chemotherapy at three participating Institution in Central Italy.
Despite considerable advances in treatment, 40 50% of patients with locally advanced disease relapse with local or distant disease progression [ 2].
However, the time to local failure differed with patients receiving sunitinib being eight times more likely to relapse locally (HR 8.06; 95% CI=1.54 42.2; P=0.004).
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