Sentence examples for localized role from inspiring English sources
The strictly perinuclear PKA-II may have a localized role not directly related to NB4 cell survival, as PKA-II-directed cAMP analog combinations failed to protect against DNR, and cAMP was fully protective in PKA-II-depleted cells.
Besides astrocytes, we also used mouse embryonic fibroblasts (MEFs) as archetypal motile cells for study of the localized role of CK-B in cell dynamics.
If constitutive binding sites for Hat1p/Hat2p at origins were identified, a localized role of Hat1p in sister chromatid cohesion may be revealed as well.
In the Bungo landscape, remaining natural forests are far from the study villages, fallows play only a very minor and localized role, and the dominant tree-based systems are oil palm and rubber monocultures.
The extent of tissue- and cell-specific expression of individual P450 isoforms has led many investigators to hypothesize localized roles in endogenous biochemical pathways for isoforms traditionally thought of as drug-metabolizing.
DOI: http://dx.doi.org/10.7554/eLife.10719.013 To further localize the role of DopR1 in KCs, we performed a rescue experiment, using a piggyBac insertion mutant, dumb 2 (Liu et al., 2012; Qin et al., 2012).
Second, we showed that the D1-like receptor DopR is required for promotion of locomotor activity elicited by acute ethanol exposure, and that its function for this role localized to the ellipsoid body.
In conclusion, our observations on a number of combinations of double mutants support our hypothesis that the whirlin complex provides a scaffold for gelsolin that appropriately localized plays a role in controlling stereocilia elongation in the apical turns of the cochlea.
This regular and distinct placement suggests a spatially localized energy/ATP production role for each mitochondrion as well as promotes intracellular homogeneity of ATP, ADP, inorganic phosphate (Pi), creatine and phosphocreatine.
This moment is purely localized moment with no role played by pz orbitals in contrast to the magnetic moment associated with single vacancy.
In many cases, it appears to play dual roles: first, it is essential for transporting particular organelles to specific locations, and second, once the organelles are appropriately localized, dynein plays a role in anchoring them there.
