Sentence examples for localized deletion from inspiring English sources

8, 9) demonstrate that localized deletion of p120 caused cadherin loss, dysplastic ameloblasts, and malformed enamel in mice that were otherwise capable of proper dental enamel formation.

This is most likely to be a localized deletion, since in contrast to Y. pestis, the GC skew pattern of the H. mustelae genome does not suggest a transposed genome region.

In C. rodentium, even ybdH and mtnE were lost, but the upstream and downstream genes are the same as in the other species in that branch indicating that this was a localized deletion.

A further utility offered by the transposon system is the possibility to revert a mutant phenotype or to generate localized deletions by transposon excision [ 23].

In the petite strains, deletions were induced in mtDNA using various mutagens but, until the advent of molecular biology, it had not been possible to characterize and localize the deletion sites.

Additionally, a three base pair deletion localized within the CCT-domain of the protein that acts as a nuclear localization signal was present in ten cultivars.

To rule out trivial explanations for these results, we verified that Aus1p and Pdr11p localized similarly in deletion and wild-type cells (data not shown) (Li and Prinz, 2004).

By exploiting the genomic information gained from the analysis of this region, a systematic screen of mutagenized wheat populations was undertaken to assess the efficiency of generating deletions localized within the 2·5 Mb region.

In the absence of donor DNA, repair of the ZFN cut-site by non-homologous end joining (NHEJ) can inactivate a gene by generating localized insertions or deletions [ 105].

Using a luciferase reporter construct, deletion analyses localized the critical segment for gene expression in mouse medullary thick ascending limb cells to 114 bp 5' of the transcription start site.

Instead these deletion constructs localized to both nuclei and cytoplasm.