The main discrepancy with RACE is due to an overestimation of the 5'-UTR size obtained using Cufflinks, probably caused by the very low coverage regions localized at the ends of the transcripts.
However, the relative κ reduction of oxidized PG is much smaller compared to that of oxidized single-crystalline graphene (SG) with the same O coverage when oxidation is localized at the GBs.
Clippet soft-launched its app in the UK early last month, and has plans to add an Android version later this summer, as well as building out additional content types beyond its current focus on delivering daily news, including events coverage, opinion pieces and localized news.
These sequencing biases were also pointed out in previous studies and can also be evidenced in the coverage profile by the presence of peaks localized in the corresponding genomic position which are separated by low-coverage regions.
We found sRNAs along all the sequence, with two peaks corresponding to two different sRNA populations at the 3′ and 5′ ends of the region: one with a coverage of more than 26,000 reads, localized in the 3′ region of the U2 snRNA (named U2-3′), anotherther, with a much lower coverage of about 1,200 reads, at the 5′ end (named U2-5′).
Localized sampling error caused by particularly low coverage in a region might therefore explain some of the anomalous regions.
However, the pathway enrichment-based method is shown to be highly non-robust when the fraction of given localized reactions decreases when it reaches 20% its coverage significantly drops to below 10%.
One option will be to double-down on the fast-growing economy of D.C. and its environs, and make the Post a comprehensive multimedia portal for the region, with localized print editions and Web pages, detailed local listings, and extensive coverage of things like crime, restaurants, and sports.
If the currently generated test cases reveal high path coverage, the Lévy flight should be localized in the sense that it reduces its diffusivity to explore nearby inputs.
The last parameter is important to reduce the "background noise" in transcriptome reconstruction, determined by the presence of single or small groups of reads localized in intergenic regions or in genes having very low coverage.
