Exact(12)
One of the protein isoforms, α-actinin 4, was found to be localized also to the nucleus in various cancer cell lines [27], [28], as well as in a differentiated skeletal muscle cell line [29].
As our analyses showed that P-gp localized also in the tubular structures forming the intravacuolar network, it is tempting to speculate that parasite P-gp is involved in the uptake of host derived lipids, either directly or via modulation of other transporters.
As described already in other cell types, DDB2 was localized strictly in the nucleus, as demonstrated by the presence of several nuclear localization signals in its amino acid sequence [23], whereas DDB1 protein, which is expressed constitutively in cells, was found to be localized also in the cytoplasm and nucleus [24].
Notably, OEP7-GFP in (co transformed cells localized also to several, relatively smaller torus structures that were devoid of myc-tagged OEP9, Toc33 or Toc34 (Figures 2c and S1b) or did not delineate the punctate/spherical fluorescent structures attributable to endogenous stromal NAGK (Figure S3).
Interestingly, p-cPLA2α was localized also in the cell membrane blebs (Fig. 8a ABC).
One gene pair (OsGRX28/ 29), which is tandemly localized, also showed divergent expression patterns with PCC value of 0.56.
Similar(48)
Total mitochondrial membrane where PNPASE localizes also showed no ribonuclease activity (Fig. 1D).
Sometimes genes co-localize also in other compartments like the endoplasmic reticulum (15), the cytoskeleton (37) or the Golgi vesicles (117).
GFP-ARTD10 co-localized also with endogenous p62, although not all ARTD10 bodies were p62 positive and vice versa.
The laminin subunits α4, α5, β1, β2 and γ1 co-localized also with CoIV, which suggests that assembled basement membrane is present in the myoepithelial compartment of the blood vessel wall.
Here, we report for the first time, that these proteins localize also to the lysosomes.
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