Sentence examples for localized administration from inspiring English sources

The present study aimed at developing a new approach for targeted delivery of drugs to cancer in general and HCC in particular, investigates the efficacy of doxorubicin direct-nano in treatment of hepatocellular carcinoma based on a rat cancer model through a localized administration by intra peritoneal route.

Localized administration of immune modulating agents has been shown to lead to regression of cutaneous melanoma metastases in several phase II studies.

The goal, procedure and possible adverse reactions of the study were explained to each patient before the study, and they were informed of the possibility of transient attendant risk of weakness and disfigurement produced by localized administration of BTX-A.

Before treatment, each patient was counseled regarding the goal, procedure, and possible adverse reactions, and they were informed of the risk of transient attendant weakness and disfigurement produced by localized administration of BTX-A.

We investigated whether localized administration of IFN-β by this bacterium could protect from experimental colitis.

CEM may also be used to monitor the localized administration of potential therapeutics.

For localized pain conditions local administration has therefore been used with positive results [22, 23].

It has been our central hypothesis that localized and controlled administration of vector in the cornea via minimally invasive simple surgical techniques would allow targeted therapeutic gene delivery into desired cells of the cornea, in vivo.

The route of administration of bleomycin is known to influence the spatial distribution and evolution of fibrotic lesions, with intratracheal administration resulting in localized bronchiocentric lesions and oropharyngeal administration, as used in our study, causing diffuse peripheral, subpleural lesions (Scotton and Chambers, 2010).

After systemic administration, PAMAM localized to the injured neurons and microglia in the brain of canines (Fig. 7b), allowing for the delivery of both NAC and valproic acid for enhanced neuroprotection [117].

Thus, localized hyperthermia after systemic administration of porphyrin labeled stealth MNPs may hold promise for future clinical therapy of melanomas.