In animal cells, the Golgi apparatus is positioned near the microtubule-organizing center, and its localization and organization depend on intact microtubules [ 10].
In other words, the ODE models neglect spatial localization and organization, such as membrane receptor clustering [3], [14].
Notwithstanding the high degree of similarity between the two proteins, the existence of the MamK-like isoform raises the question as to whether its localization and organization within AMB-1 WT cells is the same as for MamK?
Through the application of elastin-specific fluorescent dye, sulforhodamine B (SRB), the localization and organization of elastin could also be studied.
Based on bacterial artificial chromosome (BAC), expressed sequence tag (EST), and RT-PCR analyses this study provides a detailed insight into the genomic localization and organization of the mGBPs.
The method of analysis of detergent insolubility can be useful in exploring localization and organization of GPCRs in membranes and has the potential to be used in large-scale screening as well.
The establishment and analysis of the integrated physical map also led to the discovery of several important features of chromosome 6B, including the fine chromosomal localization and organization of Nor-B2 and the centromere, the gene distribution patterns and the evolutionary history of chromosomal rearrangements among grass species.
Caspase-5 homodimerization and caspase-1/-5 heterodimerization was also detected in LPS-primed primary macrophages in response to cholera toxin subunit B. The subcellular localization and organization of the inflammasome complexes varied markedly depending on the upstream trigger and on which caspase or combination of caspases were recruited.
Overall, these results indicate that N-WASP functions downstream of amph2 and dynamin 2 to regulate peripheral nuclear localization and triad organization formation during myofiber maturation.
(4) Whether intra-nuclear localization, three-dimensional organization, or epigenetic modifications of target DNA element potentially affect the binding of engineered TALE and Cas9 gRNA warrants further investigations.
Those genes are involved in responses to stimulus, auxin signaling, lipid localization and spindle organization.
