Most breast carcinomas are of epithelial origin and are either localised to the duct/lobule of origin or capable of invading surrounding stroma [ 4].
Furthermore, we have shown that four out of five of these identified taxa show strong patterns of regional geographic dominance that suggests an adaptive origin to localised ecological conditions and offers a likely mechanism in mediating their co-existence performing the same ecological role in the same fig species.
Among them, CpG oligonucleotides (ODN) are recognised by TLR9, a sensor for hypomethylated CpG sequences such as found in DNA of bacterial or viral origin, and is localised to the endosomal membrane of B cells and dendritic cells (DC) (Klinman, 2004).
Despite the high heterogeneity of the minicircle population, a conserved region has been identified, to which the origins of replication are localised.
In an attempt to summarise the available data on aetiology, three different groups may be recognised: (1) localised lesions that always have an inflammatory origin.
Midline localisation, periumbilical or poorly localised 2.
Furthermore, using immune sera raised against native haemoglobin and its fragments, as a differential diagnostic method, our technique is suitable for parallel demonstration of haemoglobin and its fragments; in this way, the origin of the bleeding can be localised (Ottó et al, 1995).
Categories are localised (stage I confined to tissue or organ of origin), regional (stage II spread to adjacent organs or tissues or stage III spread to regional lymph nodes), distant (stage IV with metastases to distant organs), or unknown stage (insufficient information available) [ 22].
However, it may be difficult to localise the site of origin of the symptoms to the gynaecological tract due to the significant overlap in symptoms and signs with gastrointestinal pathologies, and CT may be selected as the first imaging modality.
Appreciation of the close relationship between the perinephric space and adjacent retroperitoneal organs and planes can assist in localising the site of origin of pathologies and can help narrow the differential diagnosis.
