Sentence examples for localised modification from inspiring English sources
These results emphasize an involvement of hemicellulose and pectin biochemistry in wood formation, suggesting that the controlled and localised modification of these polysaccharides may define cell properties and architecture and thus, contribute to determining different biophysical characteristics of Eucalyptus wood.
Recent studies have shown that the incorporation of dGsTP into duplex DNA results in subtle localised modification on DNA structure (Somerville et al, 2003).
To compound both of these problems, ChIP-Seq produces spatially distributed patterns of binding or histone modifications localised to specific regions of the genome (peaks); this feature, in particular, renders standard differential testing methods unsuited for the comparison of ChIP-Seq data sets.
The loss of trimethylation of histone H4 in cancer cells might be a consequence of a deficiency of these enzymatic activities in tumours, and/or a lack of recruitment to heterochromatic regions, where most of the histones containing such modifications are localised.
If this were the case, the 3′ peaks of Htz1 would be expected to co-localise with histone modifications that are normally present at actively transcribed promoters.
Midline localisation, periumbilical or poorly localised 2.
This technique is based on a modification of RT-PCR methods using specific primers, one of which was localised in E7 region of viral genome and a second one which contains specific adapter sequences joined with oligo dT) [ 2, 3].
Epigenetic-mediated silencing of genes by cytosine DNA methylation in CpG islands localised in promoter regions and chromatin remodelling involving the recruitment of transcriptional corepressors and modification of histone tails is a causal event for the initiation and progression of lung cancer (Jones and Baylin, 2002; Herman and Baylin, 2003).
We did not observe any support for a modification by zinc in the multivariable-adjusted models (Pinteraction=0.32 for overall prostate cancer, 0.57 for localised, 0.76 for advanced and 0.69 for fatal prostate cancer).
Localised impacts are another concern.
