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For localised application of the dyes onto the washcloths, a dyeing solution was sprayed through a template and the washcloths later rinsed with water to remove all excess chemical reagents.
In the current study, the in vitro localised application of kainic acid to either the distal axons of motor neurons or to the motor neuron soma was achieved through culture in fluidically isolated chambers.
Prostate cryotherapy is the localised application of a freezing temperature resulting in in situ tissue ablation.
More localised application, for example to facial profile or perinasal and periorbital regions, will sometimes be more appropriate.
The spread of weedy rice seeds can be successfully prevented in crop post-planting both by panicle cutting or the localised application of systemic herbicides, but these measures should be aimed more at preventing the infestations from becoming worse, rather than reducing them.
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David Halperin has written an over-long book, more localised in its application than he seems fully to appreciate, about the aspects of being gay other than sexual choice.
For aero-elastic applications, localised stiffening can be used to replace the more destructive flutter instability that follows divergence at higher flow speeds by an extended range of divergence.
This approach is generating significant impact in the field as a result of its potential for extended localised gene delivery for applications in a variety of clinical conditions.
Our work demonstrating that VEGF189 is fully capable of engaging NRP1, in addition to its known ability to bind VEGFR1 and VEGFR2, therefore suggests that VEGF189 may be better suited than VEGF165 to induce localised tissue effects in therapeutic applications.
Deliberative theorists committed to the challenge themselves admit that theoretical solutions able to release the deliberative model (and its applications) from a "micro" (localised and local) scale, linking it up more (though not univocally) to a "macro" (generalised and global) dimension, are not easy to find.
A method for the application of PDT and controlled localised hyperthermia in a single session has previously been described by our group (Kelleher et al, 1999), and the present paper attempts to examine the antitumour benefit which might be achieved by applying the combination of a vascular-targeted PDT treatment simultaneously with HT.
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