Sentence examples for localisation specific from inspiring English sources

Our data suggest that in HGD and cancer there is an important localisation specific dysregulation of the Akt regulatory pathways but at present whether this specifically reflects increased activation or decreased deactivation cannot be determined.

The localisation of specific brain functions to specific anatomical areas is difficult.

Fast gelling hydrogels have advantageous properties for in situ applications such as localisation of specific cells and growth factors at a target area without dispersion.

When the microhybrid up-scaled to 3D thick structures, cellular localisation in specific areas of the 3D titanium structures was achieved, without decreasing overall cell proliferation compared to titanium only scaffolds.

It remains to be determined whether Lnk is required for trafficking, localisation at specific subdomains of the cortical membrane or stabilisation of InR and/or Chico.

Furthermore, by employing high-resolution multi-fluorescence microscopy, we have been able to show that the antibody localisation is specific to the abluminal surface of the vessel.

FAPP1-PH and OSBP1-PH have also been demonstrated to bind ARF1 and thus to restrict their localisation to specific membranes through the coincident detection of both Arf1 and PtdIns4 P [8].

On the contrary, most of the fluvastatin-treated cells displayed a weak anti-p21 ras immunoreaction localised mainly in the cytoplasm; no specific localisation of the p21 ras peptide was observed at the level of the plasma membranes or nuclei.

Among these proteins, some have specific localisation domains that are sufficient for their localisation to the centrosome (e.g., AKAP450, pericentrin) (Gillingham and Munro, 2000).

Thus, QDs could localise to the tumour, but the localisation was not specific for IGF1R expression.

To assess whether proteins scored as hits in our screen have a direct or indirect role in the organisation of the tER-Golgi units and whether there is a correlation between specific localisation and the BC phenotype, we expressed 6 C-terminally V5 tagged hits and examined their cellular localisation as well as any dominant negative effect on the tER-Golgi unit organisation (Table 3).