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In addition, MEK, ERK, calcineurin and NFAT4 are able to form a large molecular weight protein complex in cardiac myocytes, and although active MEK/ERK signalling did not affect NFAT at the nuclear localisation level, MEK/ERK signalling did increase DNA binding of NFAT4 (Sanna et al, 2005).
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After scanning, images were evaluated and the number and localisation (neck level) of SLNs were recorded.
Additionally, its cellular localisation and level of cellular expression do not support specific reaction within mitochondria in a way analogous to Mb [ 26].
Endogenous Armadillo was also found in nuclei, paralleling ArmS10 in localisation and levels (Figure 12).
The observation that ArmS10 modulates endogenous Armadillo at the AJ, in addition to its subcellular localisation and levels more basally, prompted us to study the effects of other Armadillo mutant proteins.
We studied cellular localisation and levels of active TGF- β1 and the activation process in gastric cancer.
Mechanistically, p53 inhibits the activity, nuclear localisation and levels of GLI1 and in turn, GLI1 represses p53, establishing an inhibitory loop.
These are therefore likely to represent the 'normal' localisation and expression level of microcephalin in cultured ovarian epithelial cells.
APC was also found to interact with hScrib and it has been suggested that Scrib controls its localisation at the level of the adherens junctions in epithelial cells.
Subgroup analyses will be performed in relation to patient compliance, type of work, adequacy of work adjustments, previous sick leaves, pain characteristics (such as localisation, duration), and level of disability at baseline.
The authors suggested that in the Z. elegans lignin formation in TEs is regulated by the localisation and activity levels of peroxidases.
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