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The reason for this localisation is unknown and future studies are required to determine which organelles the lipids are localising to.
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In 58 infants localisation was unknown.
The same sites, with an additional C5 C6 localisation, have been reported in acute non-compressive nucleus pulposus extrusion [ 26]; however, the reasons for this localisation are unknown.
The significance of PI3K-C2β expressinn in the testis and its nuclear localisation is currently unknown.
The significance of the apical localisation of these proteins in the nucleus is unknown, although this might represent discrete localisation within the nucleoli or in the perinucleolar region, since the nucleoli are apical at stage 5 (see below).
The reasons for this selective localisation of lymphatic vessels in tumours is unknown but one possibility is that they are collapsed in expanding tumours because of the high interstitial pressure.
In a majority of cases, the effects of a gene gain- or loss-of-function in specific tissues is unknown, as is the subcellular localisation of the gene product, or identity of the regulatory elements that drive its expression.
However, the subcellular localisation of GSK-3 β in renal cancer cells is unknown.
Moreover, δ- and γ-sarcoglycan seem to have an additional intracellular membrane localisation, but any contribution to muscle physiology and/or pathology is unknown (Ref. 79).
The precise function of Hspa13 is unknown but it has an intra-organellar localisation and is induced by Ca2+ release suggesting a role in ER stress and the unfolded protein response (UPR) [ 36].
Note that the maximum number of dynein motors recruited by one localisation element and the proportion of recruited motors that are actively engaged during RNP transport is unknown.
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CEO of Professional Science Editing for Scientists @ prosciediting.com