Sentence examples for localisation implies from inspiring English sources

This localisation implies that the NF1 protein directly regulates signalling at the plasma membrane during ruffling, and together with the more extensive Ras signalling during macropinocytosis, suggests that this RasGAP regulates a pool of Ras responsible for this feeding process.

Selenite-mediated disassociation of LEF1 from the CYLD promoter was not due to decreased levels of LEF1 protein or nuclear localisation, implying the specific dissociation of LEF1 from the CYLD promoter upon selenite treatment.

Their distinct tissue localisation in colorectal tumours implies that the two isoforms may orchestrate different biological functions in tumour development.

The localisation of P41/45 β-catenin with APC clusters implies that phosphorylation at Ser33, Ser37 and Thr41 by GSK3β does not result in recruitment of β-catenin to APC clusters, but instead that β-catenin resident in these complexes is phosphorylated by GSK3β in situ.

Moreover, work conducted in a human NSCLC cell line in nude mice, implies that both de-ubiquinating activity and nuclear localisation are necessary for the tumour-suppressive activity of BAP1 (Ventii et al, 2008).

This implies that the relationship between HER-2 and the subcellular localisation of p21 WAF 1/ CIP 1 is not exclusive in vitro and in vivo, but reflects a preferential cytoplasmic localisation of p21 WAF 1/ CIP 1.

This implies that oncogenic transformation affects the EPLIN/actin architecture, and thus, the localisation of EPLIN to the actin cytoskeleton may be important to exert its suppressive ability [ 7].

The diversity of Gab interaction partners also implies that there are distinct types of Gab signalosomes present in the cell, which differ in their subcellular localisation and function.

The presence of enzymic activity implies the presence of intact dimers, and we anticipate that this stability in the circulation will also allow localisation similar to that seen in ADEPT (Napier et al, 2000), a therapy now in phase I/II trial.

Guerin implies this.

It implies free will.