Sentence examples for localisation away from from inspiring English sources
This tagging strategy could mask the putative ER retention signals leading to aberrant localisation away from the ER.
A plausible mechanism is that the interaction of C35 with Syk mimics global knock-down of Syk by changing its localisation away from integrins (Zhang et al, 2009) or the nucleus (Coopman et al, 2000).
The gene clusters that are repressed by nitrogen and reside at the nuclear periphery shift in localisation away from the periphery towards the nucleus interior upon induction by nitrogen starvation (Alfredsson-Timmins et al. 2009).
Furthermore overexpression of dystroglycan was able to direct the localisation of Src away from the triton insoluble cytoskeletal fraction and into the CHAPS soluble membrane and cytoplasmic fraction.
Localisation of the enzyme in the nucleolus, away from its natural telomeric substrate, results in a nonactive telomerase.
Abnormalities in structure and function of the lysosomal compartment may promote sequestration of cisplatin away from its pharmacological target, nuclear DNA, due to incorrect localisation of transport proteins.
However, non-spherical pores may focus the deformation away from the larger pores and permit the formation of compactive localisation features through networks of misshapen pores.
Similarly, in these Csk−/− cells a palmitoylation mutant of Fyn showed redistribution away from lipid rafts and enhanced kinase activity, demonstrating that lipid raft localisation inhibits Fyn activity in the absence of Csk and independent of the presence of the negative-regulatory tyrosine Y529 [ 13].
This analysis revealed that while control cells showed that the pericentriolar satellites were closely associated with the centrosome in 90% of the cells, in the Cep126-depleted cells, the pericentriolar satellites were dispersed and located away from the centrosome in about 50% of the cells, indicating that Cep126 depletion severely affected pericentriolar-satellite localisation.
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