Sentence examples for local residues from inspiring English sources

These variations in specificity are the result of interatomic contacts with local residues near the active sites of each subunit.

The protein functions are not only determined by the interactions between local residues, but also depend on nonlocal, long-range communication between amino acids [6].

Meanwhile, the local residues of the finger domain also readjust their positions ready for catalysis.

Unfortunately, even if the number of local residues was limited at ξ = 5, 6, or  7 for both downstream and upstream, it is by no means easy to determine all the methylation sites.

Similar to the D779Y and D779W mutants, the X-ray crystal structure of D778Y shows no changes in the PRODH and P5CDH domains as only perturbations in local residues of the channel were observed.

The PresCont algorithm [ 33] combines local residue features with environmental information as input to an SVM.

Nevertheless, many studies have shown that local residue and recurrence were common after postoperative radiotherapy, primarily because of inadequate dose coverage and uneven dose distribution to the tumor-involved region [4].

A focus was a PxFG-rich domain of the Nup153 (Nup153FGPxFG) as its size permitted a combination of nuclear magnetic resonance (NMR), single molecule Förster resonance energy transfer (smFRET), and molecular dynamics (MD) simulations to characterize local, residue specific, as well as long-range implications of Importinβ binding to Nup153FGPxFG conformation and dynamics.

Overall, the lack of agreement between the experimental JHNHa couplings and those calculated from the PRE-RMD ensembles, coupled to the similarity between those calculated from the PRE-RMD and random coil ensembles, suggests that local residue-specific conformational preferences are not well reproduced in the PRE-RMD ensembles.

We have hypothesized that the van der Waals interactions between the adducts and local DNA residues could inhibit the productive hairpin intrusion.

Moreover, biochemistry would help to elaborate new models needed to understand the in vivo maintenance of CNN methylation during DNA replication, which is difficult to envisage, as there are no local cytosine residues to be methylated in the nascent complementary strand.