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Accordingly, TGF-β signaling activates small GTPases that enhance local reorganization of the actin cytoskeleton as a prerequisite for lamellipodia and filopodia formation, such as Rho, Rac and Cdc42 [31].
In addition, particular defect structures formed by local reorganization of the stacking sequence across the vacancy gap are observed and appear to be intrinsic to these van der Waals-layered compounds.
Homology modeling and MD simulations of commonly occurring activating mutations in this mutational hotspot revealed a significant local reorganization of the autoinhibited kinase conformation.
Specifically, escape from silencing of the Kcnq1 gene is accomplished by the activation of tissue-specific enhancers and involves local reorganization of higher order structure.
On the one hand, subjects with fast recovery exhibited perilesional GMV increase which corresponds to a model of local reorganization of sensorimotor representation, finally gaining a level of automatic motor behaviour.
In the absence of FANCJ, the lagging strand polymerase delta is forced to bypass the obstacle-containing Okazaki fragments, leaving behind single-stranded regions and inducing local reorganization of the chromatin.
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During the 1990s another round of local government reorganization brought a further reduction in the area of the administrative counties.
The old city and adjacent urban and rural areas were administratively merged in 1969 and later became one of Northern Ireland's 26 districts during the United Kingdom's local government reorganization in 1973.
The DFG motif at the beginning of the activation loop of the MAPK p38α undergoes a local structural reorganization upon binding of allosteric type-II and type-III inhibitors, which causes the residue F169 to move from a buried conformation (defined as DFG-in) to a solvent exposed conformation (defined as DFG-out).
Our study thus confirms recent histologic studies showing that vitamin C induces local structural reorganization processes.
The beads did not appear to induce local actin reorganization (Fig. 2).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com