Smith EL 3rd, Hung LF, Huang J ,et al. Effects of optical defocus on refractive development in monkeys: evidence for local, regionally selective mechanisms.
Potential approaches include, but are not limited to, establishing a pre-trial registry, developing site performance metrics, identifying a local regionally involved leader and bolstering recruitment incentives.
Randomized controlled trials have established concurrent chemo-radiotherapy as the preferred treatment option for inoperable local-regionally advanced head and neck squamous cell carcinomas (HNSCCs).
These authors suggest that the perioperative chemotherapy had no effect on the development of distant metastases but exhibited an advantage in eradicating viable cancer cells that were disseminated local-regionally at the time or prior to the colorectal cancer resection [ 25].
Advanced disease was defined as either locally advanced (T3-4, N0, M0), local to regionally advanced (T1-4, N1, M0), disseminated disease (T1-4, N0-1, M1) or PSA relapse after local therapy.
Current studies on functional brain networks and their alterations in brain diseases via resting-state functional magnetic resonance imaging (rs-fMRI) are generally either at local scale (regionally confined analysis and inter-regional functional connectivity analysis) or at global scale (graph theoretic analysis).
Rich Pirog, senior associate director of the C.S. Mott Group for Sustainable Food Systems, found that conventional food distribution was responsible for 5 to 17 times more CO2 than local and regionally produced food.
Notwithstanding, conclusions about emperor penguin biology and ecology in relation to environmental change are limited by a severe lack of long-term population monitoring data and associated environmental data including, inter alia, data on prey species, predation and local and regionally scaled sea ice indices.
Interpreting the household NO2 findings is complicated because it represents a mixture of local and regionally transported pollutants in Southern California.
But in Africa, a phone in every pocket has only scaled the way hyper-local and regionally fragmented markets were already communicating – through trusted referrals from family and friends, eyewitness stories, and first-hand experience.
It was also an opportunity to promote the programme locally and regionally and to initiate a network among local tutors and local/regional WHO representatives as well as the Geneva-based coordination team [ 22].
