Sentence examples for local mutations from inspiring English sources

Unexpectedly, a substantial fraction of strain-specific factor binding could not be explained by local mutations.

Local mutations affect only a small number of nucleotides and include nucleotide substitution and insertion or deletion of nucleotides.

If the dynamics of return to equilibrium are driven by local mutations involving a stepwise mutation model, then V returns to equilibrium much more slowly than HE.

This is because there are no local mutations, which could have a strong effect on small genomes.

As stated in Property 1, asymptotically, large deletions and duplications overcome local mutations and determine the spontaneous behavior.

In this regard, the later proposed web server MAGIIC-PRO simply employs rigid intra-block gaps to handle local mutations.

Third, the duplication may represent a precursor enhancing the likelihood of the substitution of a beneficial mutation through an increase in the mutational target and in local mutation rates.

The λ- μ individuals that do not undergo recombination are then mutated, according to the local mutation operator m: I → I. Mutation is performed according to a non-isotropic self-adaptive mutation rule, in the sense that each individual i has associated with it a step size for mutation (a mutation rate) for each parameter j, denoted as.

However, it remains unclear whether this high recurrence reflects positive selection, because any factors not included in our background model of the mutational process, such as local mutation hotspots, could also explain a mild excess of mutations at a given nucleotide.

Moreover, emerging concepts such as multi-parent crossover and local mutation are employed.

These observations excluded a higher local mutation rate as a major cause of greater diversity in human populations.