When an Iraqi journalist hurled a shoe at a visiting George W Bush, we were told that it was a specific local insult, with what authority, I don't know.
Given the facts that administration of live bacteria through multiple routes replicates many of the characteristics seen in acute infections such as clinical sepsis [23] while chronic infections being a local insult are usually obtained in animals using bacteria products such as LPS or fimbria or very low concentration of live bacteria.
Any case, there is a real and exciting possibility to envisage a pathway running from the normal human brain to focal epilepsy after BBB disruption induced by a local insult [ 35].
Two neuroradiologists, who were blinded to treatment arms and each other's readings, reviewed the baseline and 40-month follow-up brain MRI scans from all the hypoglycemic participants for evidence of local insult reflected by volume loss or MRI signal change.
Together, deterioration of the capacity to detoxify such materials, and the cumulative effects of oxidative stress, have been proposed to constitute a local insult to lens proteins in the ageing eye; this is considered to be a major cause of cataract formation [ 12- 14].
Some locals feel insulted by those trying to help them.
Nusa Dua, Indonesia--Contrary to conventional wisdom, warmer ocean waters are a greater threat to coral reefs than local environmental insults.
The structural pathology paradigm is guided by the inherent belief that pain and other neurophysiological changes are secondary to local structural insult to musculoskeletal structures.
There is evidence that this vasoconstriction results in a transient, local hypoxic insult in the uppermost endometrial layer at menstruation (Critchley et al., 2006; Fan et al., 2008).
These results have implications for the selection of appropriate rehabilitation techniques and may be an aetiological factor for the incidence of bilateral SIS, rather than a local mechanical insult.
