Sentence examples for local gcs from inspiring English sources

It has been demonstrated previously that the number of macrophages in RA synovial tissue is not influenced by therapy with local GCs [ 47].

As such, much research has focused on the manipulation of local GC action as a therapeutic strategy.

Intracellular GC levels are regulated by 11β-hydroxysteriod dehydrogenase (11β-HSD1) whiconvertsrts inactive cortisone to cortisol, thereby increasing local GC action.

Likewise, the distribution of Alu elements was found to have a highly positive correlation with local GC contents and the density of genes or introns (Grover et al. 2004).

As expected, the pattern of global toposite distribution appeared to reflect the local GC content.

Multi-factor clustering of P1 signals against P2 signals and local GC content clearly separated the toposites into 2 classes (Figure 4B).

To classify the toposites, significant P1 signals were subjected to cluster analysis (Ward's method) between two factors, log2 (P2/input) and local GC content around toposites.

Local GC content is a determinant factor because 1) a gene ending with a high GC content tends to extend its reading-frame; 2) a gene with low GC content regions tends to shorten its reading-frame.

We associated each nucleotide with a local GC-value.

The only potentially curative treatment for local GC is surgery.

In addition we considered possible impacts of dS, dN, gene density and the local GC content.