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Because our ChIP-seq experiments show that Scc4 directs cohesin localization to broad centromeric domains but does not affect the local distribution of cohesin peaks, we suggest that the Scc4-dependent localization pathway we discuss here is overlaid upon local determinants of cohesin positioning on chromosomes.
Here, we review and attempt to integrate these local determinants of gene expression.
Even though these signals are similar to those involved in vascular development throughout all organs and tissues of the body, the kidney has important local determinants of vessel development.
To control for the local determinants of wages, I estimate specifications that include a full set of indicators for age and education, as well as the metro-level shares of the black and white populations employed in manufacturing, the shares living on farms, and metro-average education among blacks and whites.
The strong correlation between atmospheric CO2 levels (from Antarctic ice cores) and community dynamics is somewhat surprising taking into account that, in addition to changes in global climate, the fossil diatom assemblages analyzed here were influenced by local determinants such as regional current systems, terrestrial nutrient inputs, atmospheric deposition, physical mixing, etc [31], [45].
Logistic regression analyses helped to clarify local determinants of measles vaccination.
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This argues that cancer hyper-methylation at islands is mechanistically distinct as it cannot be modeled with the same local determinant that describe methylation changes during normal development.
The most suitable design for collecting entomological parameters would be a comprehensive, prospective, longitudinal study capable of identifying local entomological determinants and transmission patterns.
Experimental and theoretical evidences suggest that local structural determinants are frequently encoded in short segments of protein sequence.
We decided therefore to use a multilevel model, and our study contributes to the existing literature by distinguishing individual as well as local government determinants in our analysis.
The interventions covered various implementation levels (national, regional or local) and determinants (physical, sociocultural, economic, political), mostly addressing both nutrition and physical activity behaviours.
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