Because our ChIP-seq experiments show that Scc4 directs cohesin localization to broad centromeric domains but does not affect the local distribution of cohesin peaks, we suggest that the Scc4-dependent localization pathway we discuss here is overlaid upon local determinants of cohesin positioning on chromosomes.
Here, we review and attempt to integrate these local determinants of gene expression.
Even though these signals are similar to those involved in vascular development throughout all organs and tissues of the body, the kidney has important local determinants of vessel development.
To control for the local determinants of wages, I estimate specifications that include a full set of indicators for age and education, as well as the metro-level shares of the black and white populations employed in manufacturing, the shares living on farms, and metro-average education among blacks and whites.
The strong correlation between atmospheric CO2 levels (from Antarctic ice cores) and community dynamics is somewhat surprising taking into account that, in addition to changes in global climate, the fossil diatom assemblages analyzed here were influenced by local determinants such as regional current systems, terrestrial nutrient inputs, atmospheric deposition, physical mixing, etc [31], [45].
Logistic regression analyses helped to clarify local determinants of measles vaccination.
Physicians' personal characteristics are considered independent of these local determinants and are not explored in this article.
These local determinants would be a second level of cohesin regulation, operating at roughly the resolution of the transcriptional units in yeast.
Customized information to ethnic groups based on sexual behaviour patterns and local determinants of transmission has rarely been given, at least not on a large scale.
This study aims at identification of the local determinants of NTD across the study area and exploration of the epidemiological implications of the findings.
