Sentence examples for local curative from inspiring English sources

In addition, local relapses and distant metastases occur even long time after local curative treatment [ 5].

(2) Salvage Lymph Node Dissection for Clinical Lymph Node Relapse after Local Curative Treatment of the Prostate.

The presence of metastatic disease excludes the patient from consideration for local curative resection intent and therefore the presence or absence of metastatic deposits should be noted.

Despite improvements in early detection, about 10 20% of men with prostate cancer present with metastatic disease, and 33% of men with early prostate cancer will develop metastases despite local curative therapies, such as surgery or radiotherapy.

Furthermore, these traditional prognostic indicators lack specificity, resulting in over-treatment of patients with potentially harmful adjuncts of negligible benefit beyond local curative resection, radiation and systemic endocrine therapy [12].

As the meta-analysis clearly indicated a 5% survival advantage of neoadjuvant cisplatin-based chemotherapy in T2 4a N0 UCB patients before local curative therapy, 24 identification of patients with high risk of unfavorable outcomes by a biomarker (for example, DAB2IP) may facilitate the use of neoadjuvant chemotherapy as early treatment of metastatic disease while the burden of disease is low.

The increased incidence of affected younger men and the downstaging effect of PSA testing have coincided with the development of radical local treatments with curative intent on locally confined cancer.

1 Although the majority (85%) of CRC patients in developed countries can undergo initially curative local resection, 2 leading causes of death are local recurrence and metastatic disease.

Part 1: screening, diagnosis, and local treatment with curative intent.

Second primary tumors (SPTs) have emerged as an increasingly important problem, despite curative local therapy, underscoring the principle of field cancerization.

Salvage radical prostatectomy (SRP) for radiorecurrent prostate cancer (PCa) is a second local treatment with curative intent in patients with true organ-confined recurrent PCa.