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The present study aims at providing the rationale for the design of new research protocols evaluating the efficacy of local antibiotics for infected pancreatic necrosis.
Local antibiotics, such as vancomycin, have been used in combination with fusion materials over the past decade to decrease infection risk.
We hypothesized that a group of patients given an intra-articular, intraoperative injection of gentamicin would report a lower infection rate than a group without local antibiotics.
The evidence for use of local antibiotics is not strong.
Superficial infection was controlled with local antibiotics and regular dressings.
Local antibiotics are commonly delivered via cement beads and spacers.
Similar(8)
Local antibiotic beads allow the delivery of high antibiotic concentrations locally with very low levels in the systemic circulation [15].
If drainage is required, local administration of antibiotics through transmural nasocystic or percutaneous catheter may allow increasing local antibiotic concentrations.
Therefore, the mPEG-PLCPPA hydrogel shows promise as an injectable local antibiotic delivery system.
Overall, this cost-effective technique provided efficient local antibiotic delivery, early mobilization, facilitation of reimplantation, and improved patient satisfaction.
The aim of this study was to assess the efficacy of local antibiotic policy in a Tunisian ICU.
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