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The idea of artificially loading down that sensible exploration policy with sharply restrictive gasoline mileage standards, however, makes none at all.
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Like PTH, bone loading down-regulates Sost/sclerostin expression within osteocytes [6 10], whereas unloading increases its production [7,11].
In contrast, in tibiae from ERα−/− mice loading down-regulated the expression of electron transport-related genes (Ndufa11 (− 1.7-fold), Ndufa12 (− 1.7-fold) and oxoglutarate dehydrogenase (Ogdh, − 1.7-fold).
The car was loaded down with boxes.
He's a load down there.
Soldiers, loaded down with gear, had simply disappeared.
Banks found themselves loaded down with non-performing loans.
By 9 a.m., they had finished shopping and were loaded down with their morning groceries.
FPA Capital, which reopens with a 5.25percentt load, down from 6.5percentt, has outstanding long-term returns.
"Was loaded down with those darn mags again today," another wrote.
None of the items are loaded down with windbag descriptions of ingredients or preparation details.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com