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A portion of the slabs were loaded successively until failure, whereas others were loaded only once.
This approach was used in both DOVIS and Autodock4.lga.MPI (with maps repackaged into an efficient binary format), with significant decreases in I/O observed when grid maps are loaded only once for each node [13, 17].
Since the three methods are combined into one executable, the structure data for each protein domain is loaded only once and reused whenever the domain appears in a pairwise comparison being performed.
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The same bandwidth pattern KB.bw is applied on both directions of the kiosk/bus link, that is, pipes 1 and 2. The contacts trigger pattern KB.trg is loaded only on pipe 1, but once the DTN2 TCP convergence layer discovers a contact on the forward direction, it automatically "discovers" the contact also on the reverse direction.
Despite the fact that Brazilian HIV treatment guidelines stipulate routine viral load and CD4+ T-cell count testing every three to four months for patients on ART, most patients received viral load testing only once per year (median of 1 [0.8, 1] viral load measurement per patient per year).
Here we truly profited form using immutable objects: Using the Flyweight pattern keeps the memory footprint of our molecules low while letting us store a lot of additional information for all isotopes and elements that has to be loaded and calculated only once.
As discussed above, we modified the AutoDock 4.0 source code to implement a strategy where multiple ligands are docked by loading the energy grids only once.
It would be ideal to load all energy grids only once to dock an entire block of ligands instead of repeating the I/O file operation for each ligand.
Hence, to improve runtime efficiency and reduce I/O file operations, we modified the AutoDock 4.0 source code to load the energy grid files only once, while docking multiple ligands in a single run.
Leg extensor muscle strength are quantitatively assessed using the one-repetition maximum (1RM) technique and are defined as the maximum load that could be moved only once throughout the full range of motion (ROM) while maintaining proper form [ 64].
That is, the internal state of an agent will usually be read only once: when the web page is loaded and the agent is started.
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