Aggrecan interacts with hyaluronic acid, forming large aggregates, which are entrapped in the collagen network, and provide cartilage its osmotic properties, giving cartilage its ability to resist compressive loads review in [ 9].
Mcm2-7 complexes are loaded (reviewed in Remus and Diffley, 2009) to encircle double-stranded DNA (dsDNA) via a 'gate' between Mcm2 and Mcm5 (Bochman and Schwacha, 2007, 2008; Costa et al., 2011) to yield a double hexamer (Evrin et al., 2009; Remus et al., 2009) that does not unwind DNA.
Some of the invited sites declined to participate in the study, and the reasons provided were tracked and included lack of adequate staff resources, current project load, institutional review board (IRB) concerns (primarily at academic sites), and other priorities of the sites (for example, transitioning to electronic medical records).
He continued dealing with a heavy load of reviewing and editing long after his formal retirement.
She was accused by many scholars of politicizing the endowment's grant-making by favoring traditional over multicultural projects and loading peer review committees with conservatives.
I front-loaded the review with all the nerdy stuff – this is who [director] Dan O'Bannon is, this is the film's relationship with the George Romero Living Dead movies – it was almost certainly 180 words of utterly nerdy, genre cross-referencing.
In fact, scientists who are given grant proposals to scrutinize are under strict dictate not to reveal the content of the proposals or share the load of reviewing them.
I tried to front-load this review with praise, because once you read a bare-bones summary of "Awake's" premise, you might run away.
Mutations in the gene encoding hepcidin (HAMP) or upstream regulators of hepcidin such as hemojuvelin (HJV), HFE and transferrin receptor 2 (TFR2) lead to low levels of circulating hepcidin in relation to iron stores and consequent iron loading [for review see 22].
This resembles the alterations in the level of costamere components observed in both rats and humans with reduced load bearing (reviewed in [ 27, 30, 31]).
